MDR-1A mutation in the MDR-1 gene causes sensitivity to certain drugs. This mutation causes a defect in the P-glycoprotein that is normally responsible for transporting certain drugs out of the brain leading to a buildup of these toxins. A build up of these toxins can cause neurological symptoms such as, seizures, ataxia, or even death. Please note that even one copy of this mutation can cause sensitivity, just normally at a higher dose. (For a list of MDR sensitive drugs please see below)

DMDegenerative Melopothy is a progressive neurological disorder that affects the spinal cord of dogs. Dog with two copies of the defective gene can experience a breakdown of the cells responsible for sending and receiving signals from the brain.

CRM-1CRM-1 is a mutation that causes raised lesions to form on the retina. These lesions alter the appearance of the eye but does not affect sight. The lesions may disappear, or may result in minor retinal folding.

CDCD is a disease that causes degeneration of the retinal "cones" that respond primarily to bright daylight, resulting in day-blindness.

PRAPRA is when the cells in the dogs retina degenerate and die. Most dogs will not show signs of vision loss until 3-5 years of age and complete blindness in older dogs.

CEACEA is a bilateral eye disease common in aussies. This disorder causes abnormal development in layers of tissue in the eye under the retina called the choroid.

HUUHUU is a genetic mutation that metabolizes waste products as uric acid in their urine. The uric acid forms into hard stones in the bladder causing pain and inflammation as the stone moves through the urinary tract.

HCHC is the clouding of the lens of the eye caused by the breakdown of tissue in the eye. This can cause an inability to see clearly and can cause total blindness. Your dog only needs one mutation to have this appear later in life. Please note that not all cataracts are hereditary. Cataracts can also be caused by old age or injury.

Breed TestMany genetic tests are now advertising "Breed Tests" to see what breed your dog and its ancestors are. These are based off of what people claim and are known to be inaccurate on pure breed dogs. Although it's fun to see how these results turn out there is some degree of error so even a fully purebred dog will not always test as 100% purebred.

Other TestingOther/Unnecessary Tests - These companies provide generic DNA testing panels that aren't suited to any breed in particular. They test for several gene traits that might exist it one breed but not another. It's not so much that those tests don't provide value to all dogs but we work exclusively with Austrailian Shepherds and those traits don't apply to our breed, making these options not as cost effective as others.
* No wasted tests - Animal Genetics offers specific DNA panels per breed so they're only testing for traits that apply to the breed you've chosen, making your money go further and results more valuable.

Merle GeneIn most cases you will be able to tell you have a Merle pup due to the merle coloring but in some rare cases you can have what is called a Cryptic or Phantom Merle where your pup is not of merle coloring but still carries the gene. We offer this test for people who are looking to breed to ensure there is no opportunity to breed a double merle pup. This is mandatory if you're looking to breed.

Bobtail GeneThe bobtail gene is what causes aussies to be born with a naturally bobbed tail. We offer this as a test for breeders due to the fact that breeding two dogs with this gene is lethal in utero and can cause reduced litter sizes.

MDR-1A mutation in the MDR-1 gene causes sensitivity to certain drugs. This mutation causes a defect in the P-glycoprotein that is normally responsible for transporting certain drugs out of the brain leading to a buildup of these toxins. A build up of these toxins can cause neurological symptoms such as, seizures, ataxia, or even death. Please note that even one copy of this mutation can cause sensitivity, just normally at a higher dose. (For a list of MRD sensitive drugs please see below)

DMDegenerative Melopothy is a progressive neurological disorder that affects the spinal cord of dogs. Dog with two copies of the defective gene can experience a breakdown of the cells responsible for sending and receiving signals from the brain.

CRM-1CRM-1 is a mutation that causes raised lesions to form on the retina. These lesions alter the appearance of the eye but does not affect sight. The lesions may disappear, or may result in minor retinal folding.

CDCD is a disease that causes degeneration of the retinal "cones" that respond primarily to bright daylight, resulting in day-blindness.

PRAPRA is when the cells in the dogs retina degenerate and die. Most dogs will not show signs of vision loss until 3-5 years of age and complete blindness in older dogs.

CEACEA is a bilateral eye disease common in aussies. This disorder causes abnormal development in layers of tissue in the eye under the retina called the choroid.

HUUHUU is a genetic mutation that metabolizes waste products as uric acid in their urine. The uric acid forms into hard stones in the bladder causing pain and inflammation as the stone moves through the urinary tract.

HCHC is the clouding of the lens of the eye caused by the breakdown of tissue in the eye. This can cause an inability to see clearly and can cause total blindness. Your dog only needs one mutation to have this appear later in life. Please note that not all cataracts are hereditary. Cataracts can also be caused by old age or injury.

Merle GeneIn most cases you will be able to tell you have a Merle pup due to the merle coloring but in some rare cases you can have what is called a Cryptic or Phantom Merle where your pup is not of merle coloring but still carries the gene. We offer this test for people who are looking to breed to ensure there is no opportunity to breed a double merle pup. We offer this as a test for both our pups and your potential breeder pup as well. This is mandatory if looking to breed.

n/nn/n indicates non-dominant and non-recessive gene trait. Kovu is fully cleared with no MDR-1 at all.

n/M1n/M1 indicates non-dominant and recessive carrier gene trait. This marker indicates that the dog is a recessive gene trait carrier. They can pass this onto their puppies.

n/M1n/M1 indicates non-dominant and recessive carrier gene trait. This marker indicates that the dog is a recessive gene trait carrier. They can pass this onto their puppies.

n/M1n/M1 indicates non-dominant and recessive carrier gene trait. This marker indicates that the dog is a recessive gene trait carrier. They can pass this onto their puppies.

n/nn/n indicates non-dominant and non-recessive gene trait. Aries is fully cleared with no MDR-1 at all.